Exosomal circHIPK3 derived from umbilical cord-derived mesenchymal stem cells enhances skin fibroblast autophagy by blocking miR-20b-5p/ULK1/Atg13 axis.

Zhi-Yang QiuShi-Shuai LinNan-Fang PanZhi-Hu LinYun-Chuan PanZun-Hong Liang

Published in: Journal of diabetes investigation (2023)

UCMSCs-derived exosomal circHIPK3 promoted cell autophagy and proliferation and accelerated the fibroblast injury repair by the miR-20b-5p/ULK1/Atg13 axis.

Keyphrases

umbilical cord
mesenchymal stem cells
signaling pathway
cell death
endoplasmic reticulum stress
wound healing
oxidative stress
cell therapy
single cell
soft tissue
stem cells
bone marrow