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A novel GIT2-BRAF fusion in pilocytic astrocytoma.

Jeffrey HelgagerHart G LidovNavin R MahadevanMark W KieranKeith L LigonSanda Alexandrescu
Published in: Diagnostic pathology (2017)
GIT2-BRAF fusion has not been reported in the literature in any tumor. Given that the BRAF sequence deleted is identical to that seen in other fusion events in PA, it most likely acts as tumor driver by activation of the MAPK pathway.
Keyphrases
  • metastatic colorectal cancer
  • wild type
  • systematic review
  • signaling pathway
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  • pi k akt
  • amino acid