Sustained density of neuroendocrine cells with aging precedes development of prostatic hyperplasia in spontaneously hypertensive rats.

Yuki KyodaKoji IchiharaKohei HashimotoKo KobayashiFumimasa FukutaNaoya Masumori

Published in: BMC urology (2019)

In the natural history of BPH, NE cells may play an important role in the initial development of BPH because sustained density of NE cells in the VPd precedes the development of prostatic hyperplasia.

Keyphrases

induced apoptosis
cell cycle arrest
benign prostatic hyperplasia
prostate cancer
oxidative stress
lower urinary tract symptoms
signaling pathway