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Prenatal alcohol and cannabis exposure can have opposing and region-specific effects on parvalbumin interneuron numbers in the hippocampus.

Hannah M O ReidTaylor M SnowdenIrene ShkolnikovKristen R BreitCristina RodriguezJennifer D ThomasBrian R Christie
Published in: Alcoholism, clinical and experimental research (2021)
Prenatal exposure to alcohol and THC differentially affects parvalbumin-positive interneuron numbers in the hippocampus, indicating that both individual and combined exposure can impact the balance of excitation and inhibition in a structure critically involved in learning and memory processes.
Keyphrases
  • pregnant women
  • cerebral ischemia
  • cognitive impairment
  • blood brain barrier
  • brain injury