The effect of low-dose corticosteroids and theophylline on the risk of acute exacerbations of COPD: the TASCS randomised controlled trial.

Christine R JenkinsFu-Qiang WenAllison MartinPeter J BarnesBartolome R CelliNan-Shan ZhongJin-Ping ZhengAnish ScariaGian Luca Di TannaThomas BradburyNorbert Berendnull null

Published in: The European respiratory journal (2021)

Low-dose theophylline alone or in combination with prednisone did not reduce exacerbation rates or clinically important secondary end-points compared with placebo.

Keyphrases

low dose
chronic obstructive pulmonary disease
high dose
lung function
liver failure
respiratory failure
study protocol
drug induced
double blind
aortic dissection
intensive care unit
extracorporeal membrane oxygenation
mechanical ventilation
open label