TREM2 regulates obesity-induced insulin resistance via adipose tissue remodeling in mice of high-fat feeding.
Can LiuPinhao LiHui LiSicong WangLifeng DingHanbin WangHui YeYue JinJinchao HouXiangming FangQiang ShuPublished in: Journal of translational medicine (2019)
Trigger receptor expressed on myeloid cells 2 may function as a feedback mechanism to curb obesity-induced insulin resistance via regulating adipose tissue remodeling.
Keyphrases
- insulin resistance
- adipose tissue
- high fat diet induced
- high fat diet
- metabolic syndrome
- skeletal muscle
- polycystic ovary syndrome
- type diabetes
- high glucose
- diabetic rats
- induced apoptosis
- drug induced
- glycemic control
- dendritic cells
- acute myeloid leukemia
- bone marrow
- weight loss
- immune response
- signaling pathway
- oxidative stress
- cell death
- weight gain
- endothelial cells
- body mass index