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Enhancing respiratory function in neuromuscular disease: the role of non-invasive ventilation. A narrative review.

Paolo BanfiAgata Alba Maria Domenica BuscemiElena CompalatiMartina PisoniMarco ManteroAgata Lax
Published in: Acta myologica : myopathies and cardiomyopathies : official journal of the Mediterranean Society of Myology (2024)
Neuromuscular diseases (NMDs) comprise a heterogeneous group of conditions characterized by extreme progressive muscle weakness leading to respiratory failure. Noninvasive mechanical ventilation (NIV) has emerged as a cornerstone in the management of respiratory complications associated with NMDs. This review aims to elucidate the role of NMV in respiratory function, improving quality of life, and prolonging survival in individuals with NMD. The physiological basis of respiratory impairment in NMDs, principles of NMV application, evidence supporting its efficacy, patient selection criteria, and potential challenges in its application are discussed.
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