Antioxidative effect of Periplaneta americana extract on dextran sulfate sodium-induced ulcerative colitis through activation of the Nrf2 signal.

Jianzhong Wu Zhen Zhang Qimei Wu Linli Zhang Zhipeng ChenHairong ZhaoXiumei Wu Yu Zhao Cheng-Gui Zhang Jian Ge Heng Liu

Published in: Pharmaceutical biology (2023)

PAE may relieve oxidative stress through the Nrf2 signaling pathway, and proline and glycine may be used as active components of its antioxidative stress activity.

Keyphrases

oxidative stress
diabetic rats
ulcerative colitis
signaling pathway
induced apoptosis
anti inflammatory
dna damage
ischemia reperfusion injury
high glucose
pi k akt
epithelial mesenchymal transition
drug induced
heat shock
cell proliferation
endothelial cells