A protocol for remote collection of skeletal muscle mass via D3-creatine dilution in community-dwelling postmenopausal women from the Women's Health Initiative.
Hailey R BanackJean Wactawski-WendeHeather M Ochs-BalcomElizabeth M Cespedes FelicianoBette CaanCatherine LeeGarnet AndersonMahalakshmi ShankaranWilliam J EvansPublished in: PloS one (2024)
The D3Cr method will transform our ability to measure muscle mass in large-scale epidemiologic research. This study is an opportunity to advance our understanding of a key source of morbidity among older and long-term female cancer survivors. This project will fill knowledge gaps, including the antecedents and consequences of low muscle mass, and use innovative methods to overcome common sources of bias in cancer research. The results of this study will be used to develop interventions to mitigate the harmful effects of low muscle mass in older adults and promote healthy survivorship in cancer survivors in the old (>65) and oldest-old (>85) age groups.
Keyphrases
- postmenopausal women
- skeletal muscle
- healthcare
- community dwelling
- young adults
- physical activity
- quality improvement
- public health
- childhood cancer
- mental health
- squamous cell carcinoma
- type diabetes
- pregnant women
- papillary thyroid
- health information
- polycystic ovary syndrome
- pregnancy outcomes
- body composition
- liquid chromatography tandem mass spectrometry
- liquid chromatography
- social media
- lymph node metastasis