Anti-vinculin antibodies in scleroderma (SSc): a potential link between autoimmunity and gastrointestinal system involvement in two SSc cohorts.

Yossra Atef SulimanSuzanne KafajaSunny J OhMohamed AlemamGianluca BagnatoGiuseppina AbignanoRam Raj SinghGillian BarlowXiaochen LiuIsela ValeraWalter MoralesAli RezaieMark PimentelFrancesco Del GaldoDaniel E Furst

Published in: Clinical rheumatology (2020)

• Anti-vinculin antibodies are elevated in systemic sclerosis and are relatively common. • In these SSc patients, anti-vinculin antibodies are associated with higher levels of GI symptoms in SSc. • A potential link between anti-vinculin antibodies and vascular system involvement was shown.

Keyphrases

systemic sclerosis
interstitial lung disease
end stage renal disease
newly diagnosed
ejection fraction
rheumatoid arthritis
climate change