Modulation of the activation of endothelial nitric oxide synthase and nitrosative stress biomarkers by aspirin triggered lipoxins: A possible mechanism of action of aspirin in the antiphospholipid syndrome.

Manuel Granada-GómezManuela Velásquez-BerríoCarolina Rúa MolinaSebastián San MartínCarlos EscuderoAngela M AlvarezAngela P Cadavid

Published in: American journal of reproductive immunology (New York, N.Y. : 1989) (2023)

Increased nitrosative stress present in serum of women with SN-OAPS is associated with IgG-mediated impaired endothelial NO synthesis in endothelial cells. ATL prevent these cellular changes.

Keyphrases

endothelial cells
nitric oxide synthase
low dose
nitric oxide
cardiovascular events
antiplatelet therapy
high glucose
stress induced
vascular endothelial growth factor
acute coronary syndrome
anti inflammatory drugs
cardiovascular disease
heat stress
percutaneous coronary intervention
atrial fibrillation