CD-CODE: crowdsourcing condensate database and encyclopedia.
Nadia RostamSoumyadeep GhoshChi Fung Willis ChowAnna HadarovichCedric LandererRajat GhoshHongKee MoonLena HersemannDiana M MitreaIsaac A KleinAnthony A HymanAgnes Toth-PetroczyPublished in: Nature methods (2023)
The discovery of biomolecular condensates transformed our understanding of intracellular compartmentalization of molecules. To integrate interdisciplinary scientific knowledge about the function and composition of biomolecular condensates, we developed the crowdsourcing condensate database and encyclopedia ( cd-code.org ). CD-CODE is a community-editable platform, which includes a database of biomolecular condensates based on the literature, an encyclopedia of relevant scientific terms and a crowdsourcing web application. Our platform will accelerate the discovery and validation of biomolecular condensates, and facilitate efforts to understand their role in disease and as therapeutic targets.