A 72-year-old man sought care for a cognitive deterioration over the past 5 years. There was a documented decline in his performance on the Mini-Mental State Examination (30 of 30 in 2016, 23 of 30 in 2021), with mainly episodic memory impairment. A more detailed history revealed a gait problem, paresthesia in both feet, and nocturnal urinary frequency. Clinical examination findings were suggestive of a length-dependent polyneuropathy. In addition, a right-sided Babinski sign was noted. Electromyography and a nerve conduction study corroborated a peripheral axonal sensorimotor neuropathy. MRI of the brain was performed (Figure).
Keyphrases
- healthcare
- spinal cord injury
- palliative care
- blood pressure
- obstructive sleep apnea
- mental health
- white matter
- working memory
- contrast enhanced
- single cell
- magnetic resonance
- resting state
- diffusion weighted imaging
- computed tomography
- sleep apnea
- sleep quality
- pain management
- depressive symptoms
- physical activity
- cerebral palsy
- health insurance