Maternal type 1 diabetes, preterm birth, and risk of intellectual disability in the offspring: A nation-wide study in Sweden.

Martina Persson Kristina Tedroff Weiyao Yin Mikael Andersson Franko Sven Sandin

Published in: European psychiatry : the journal of the Association of European Psychiatrists (2024)

T1D in pregnancy is associated with moderately increased risks of ID in the offspring. The risk is largely mediated by preterm birth, in particular for moderate/severe cases of ID. There was no support for risk-modification by maternal HbA1c.

Keyphrases

preterm birth
intellectual disability
gestational age
birth weight
low birth weight
type diabetes
autism spectrum disorder
high fat diet
pregnancy outcomes
insulin resistance
pregnant women
adipose tissue
glycemic control
weight gain
body mass index
climate change