Rodent models for nicotine withdrawal.

Ranjithkumar ChellianAzin Behnood-RodDawn M BruijnzeelRyann WilsonVijayapandi PandyAdriaan W Bruijnzeel

Published in: Journal of psychopharmacology (Oxford, England) (2021)

The nicotine withdrawal symptoms that are observed in rodents are similar to those observed in humans. Tobacco smoke and e-cigarette aerosol contain chemicals and added flavors that enhance the reinforcing properties of nicotine. Therefore, more valid animal models of tobacco and e-cigarette use need to be developed by using tobacco smoke and e-cigarette aerosol exposure methods to induce dependence.

Keyphrases

smoking cessation
depressive symptoms