Single-nucleotide polymorphism rs10036727 in the SLIT3 gene is associated with osteoporosis at the femoral neck in older Mexican postmenopausal women.

Alberto Hidalgo-BravoCristina Hernández-MedranoRosalba Sevilla-Montoya Berenice Rivera-Paredez Eric Gustavo Ramirez-Salazar Jeny Flores-Morales Nelly Patiño Jorge Salmerón Margarita Valdés-Flores Rafael Velázquez-Cruz

Published in: Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology (2020)

Our results provide new evidence regarding a possible involvement of SLIT3 in bone metabolisms and encourage the development of more studies in different populations to support these observations.

Keyphrases

postmenopausal women
bone mineral density
genome wide
physical activity
copy number
community dwelling
middle aged
case control
body composition
genome wide identification
dna methylation
genetic diversity
gene expression
bone regeneration
transcription factor
bone loss