Cell-free circulating tumor DNA in colorectal cancer: a proof of concept with simplified methodology.
Javier BosqueCarlos GuiraoAsia FerrándezNoelia SuarezMaria Isabel CastillejoDiana AnguitaMaría PamiesAlejandro MoyaJosé Luis SotoJavier Gallego PlazasPublished in: Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico (2022)
This exploratory analysis of cfDNA based on fluorometry and electrophoresis methods showed promising results discriminating colorectal cancer and non-cancer patients, as well as different colorectal cancer stages and disease profiles. Further studies are needed to increase our knowledge and to help to overcome barriers to broader implementation and applications.