Establishment and characterization of patient-derived head and neck cancer models from surgical specimens and endoscopic biopsies.
Daniel StrüderTheresa MomperNina IrmscherMareike KrauseJan LieseSebastian SchravenAnnette ZimpferSarah ZonnurAnn-Sophie BurmeisterBjörn SchneiderBernhard FrerichRobert MlynskiChristina Große-ThieChristian JunghanssClaudia MaletzkiPublished in: Journal of experimental & clinical cancer research : CR (2021)
Including biopsy samples from locally advanced or metastatic lesions from patients with non-surgical treatment strategies, increases the availability of PDX for basic and translational research. This facilitates (pre-) clinical studies for individual response prediction based on immunological biomarkers.