Silencing MR-1 Protects against Myocardial Injury Induced by Chronic Intermittent Hypoxia by Targeting Nrf2 through Antioxidant Stress and Anti-Inflammation Pathways.

Qixue WangYue WangJiner ZhangShuo PanShaofeng Liu

Published in: Journal of healthcare engineering (2022)

Our research results demonstrate that silencing MR-1 rescued the myocardium the injury from inflammatory and oxidative stress in CIH-induced rats by administration of the Nrf2 signaling pathway.

Keyphrases

oxidative stress
diabetic rats
induced apoptosis
signaling pathway
contrast enhanced
ischemia reperfusion injury
dna damage
magnetic resonance
high glucose
endothelial cells
pi k akt
drug induced
epithelial mesenchymal transition
magnetic resonance imaging
stress induced
heat shock
endoplasmic reticulum stress