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Molecular Mechanism of Jinchan Oral Liquid in the Treatment of Children with Respiratory Syncytial Virus Pneumonia Based on Network Pharmacology and Molecular Docking Technology.

Li ShenYiguo JiangJinmiao LuGuangfei WangXiaolan ZhangSumei HeCheng WangZhi-Ping Li
Published in: BioMed research international (2021)
In this study, we preliminarily discussed the main active ingredients, related targets, and pathways of JOL and predicted the pharmacodynamic basis and the potential therapeutic mechanisms of RSV pneumonia. In summary, the network pharmacology strategy may be helpful for the discovery of multitarget drugs against complex diseases.
Keyphrases
  • respiratory syncytial virus
  • molecular docking
  • molecular dynamics simulations
  • small molecule
  • young adults
  • high throughput
  • respiratory failure
  • ionic liquid
  • mechanical ventilation