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Recent advances in the chemistry of 2-chloroquinoline-3-carbaldehyde and related analogs.

Wafaa S HamamaMona E IbrahimAyaa A GoodaHanafi H Zoorob
Published in: RSC advances (2018)
This review highlights the recently cited research data in the literature on the chemistry of 2-chloroquinoline-3-carbaldehyde and related analogs and their applications over the period from 2013 to 2017. It covers: synthesis of quinoline ring systems and reactions adopted to construct fused or binary quinoline-cord heterocyclic systems. The biological evaluation and the synthetic applications of the target compounds were illustrated.
Keyphrases
  • molecular docking
  • systematic review
  • drug discovery
  • machine learning