Unmasking pneumococcal carriage in a high HIV prevalence population in two community cohorts with a high prevalence of HIV in South Africa, 2016-2018: the PHIRST study.
Maimuna CarrimStefano TempiaDeus ThindwaNeil A MartinsonKathleen KahnStefan FlascheOrienka HellfersceeFlorette K TreurnichtMeredith L McMorrowJocelyn MoyesThulisa MkhenceleAzwifarwi MathunjwaJackie KleynhansLimakatso LebinaKatlego MothlaolengFloidy WafawanakaFrancesc Xavier Gómez-OlivéCheryl CohenAnne von GottbergNicole Wolternull nullPublished in: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America (2022)
We observed high levels of pneumococcus colonization across all age groups. Children and people living with HIV were more likely to be colonized and had higher pneumococcal loads. Carriage duration decreased with age highlighting that children remain important in pneumococcal transmission.