Therapeutic effect of adipose-derived mesenchymal stem cells in a porcine model of abdominal sepsis.

J F Vélez-PintoMariano García-ArranzD García-BernalS García Gómez-HerasP Villarejo-CamposA M García-HernándezL Vega-ClementeS Jiménez-GalanesH GuadalajaraJ M MoraledaD García-Olmo

Published in: Stem cell research & therapy (2023)

Intraperitoneal administration of ADSCs as an adjuvant therapy for sepsis improves the outcome and diminishes the effects of peritonitis and associated organ damage by regulating the immune system and reducing intra-abdominal adhesions in a clinically relevant porcine model of abdominal sepsis.

Keyphrases

septic shock
acute kidney injury
intensive care unit
mesenchymal stem cells
early stage
umbilical cord
bone marrow
stem cells