Thigh muscle composition changes in knee osteoarthritis patients during weight loss: Sex-specific analysis using data from osteoarthritis initiative.
Kamyar MoradiBahram MohajerSoheil MohammadiAli GuermaziHamza Ahmed IbadFrank W RoemerXu CaoThomas M LinkShadpour DemehriPublished in: Osteoarthritis and cartilage (2024)
In participants with KOA and 4-year weight loss, the longitudinal changes in thigh muscle quality were overall beneficial but to a less degree in females compared to males. Further research is warranted to investigate the underlying mechanisms and develop sex-specific interventions to optimize muscle quality during weight loss.
Keyphrases
- weight loss
- knee osteoarthritis
- bariatric surgery
- roux en y gastric bypass
- skeletal muscle
- end stage renal disease
- gastric bypass
- quality improvement
- newly diagnosed
- ejection fraction
- chronic kidney disease
- physical activity
- peritoneal dialysis
- prognostic factors
- weight gain
- type diabetes
- obese patients
- soft tissue
- metabolic syndrome
- adipose tissue
- insulin resistance
- deep learning
- machine learning