The effect of probiotics on functional constipation in adults: A randomized, double-blind controlled trial.

Fabiana Cristina Rosa MitelmãoKarin HäckelCristiane de Cássia BergamaschiMarli GerenuttiMarcus Tolentino SilvaVictor Manuel BalcãoMarta Maria Duarte Carvalho Vila

Published in: Medicine (2022)

The two probiotic cocktails were effective in improving the symptoms of functional constipation, by increasing both the weekly frequency of evacuation and stool quality, and were deemed safe. Clinicaltrials.gov number: NCT04437147.

Keyphrases

double blind
irritable bowel syndrome
clinical trial
study protocol
placebo controlled
open label
depressive symptoms
phase iii
sleep quality