Draft genome of the Klebsiella pneumoniae 24Kpn33 and complete sequence of its pCOL-1, a plasmid related to the bla KPC-2 acquisition in Pseudomonas aeruginosa .

Deisy AbrilDuway Nicolas Lesmes-LeonRicaurte Alejandro Marquez-OrtizAura Lucía LealCatalina Tovar-AceroZayda Lorena Corredor RozoNatasha Vanegas GómezJavier Escobar-Pérez

Published in: Microbiology resource announcements (2024)

We report the draft genome of a clinical multi-resistant Klebsiella pneumoniae (24Kpn33) isolate, whose genome (5.7 Mbp) harbored 17 antibiotic resistance genes, including bla KPC-2 . Notably, this gene was mobilized within the IncP-6 pCOL-1 plasmid, the first genetic platform related to the acquisition and dissemination of the bla KPC-2 in Pseudomonas aeruginosa .

Keyphrases

klebsiella pneumoniae
escherichia coli
pseudomonas aeruginosa
genome wide
multidrug resistant
antibiotic resistance genes
biofilm formation
cystic fibrosis
acinetobacter baumannii
copy number
microbial community
dna methylation
wastewater treatment
crispr cas
gene expression
anaerobic digestion
candida albicans