Plasma and cerebrospinal fluid concentrations of cefiderocol during successful treatment of carbapenem-resistant Acinetobacter baumannii meningitis.
Wesley D KufelYasmeen AbouelhassanJeffrey M SteeleRamiro L GutierrezTalha PerwezGeorge BourdagesDavid P NicolauPublished in: The Journal of antimicrobial chemotherapy (2022)
Cefiderocol, when given as 2 g q8h and 2 g q6h, attained CSF concentrations that exceeded the organism-specific MIC and the CLSI susceptible breakpoint (≤4 mg/L) for 100% of the dosing interval.