Holographic characterization of colloidal fractal aggregates.

Chen WangFook Chiong CheongDavid B RuffnerXiao ZhongMichael D WardDavid G Grier

Published in: Soft matter (2018)

In-line holographic microscopy images of micrometer-scale fractal aggregates can be interpreted with an effective-sphere model to obtain each aggregate's size and the population-averaged fractal dimension. We demonstrate this technique experimentally using model fractal clusters of polystyrene nanoparticles and fractal protein aggregates composed of bovine serum albumin and bovine pancreas insulin.

Keyphrases

type diabetes
optical coherence tomography
high resolution
deep learning
high throughput
convolutional neural network
metabolic syndrome
protein protein
glycemic control
insulin resistance
label free