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Chemical Constituents and Pharmacological Properties of Frankincense: Implications for Anticancer Therapy.

Yong-Rong WuWei XiongYing-Jing DongXin ChenYuan-Yuan ZhongXin-Ling HeYu-Jia WangQun-Fang LinXue-Fei TianQing Zhou
Published in: Chinese journal of integrative medicine (2024)
The discovery of novel antitumor agents derived from natural plants is a principal objective of anticancer drug research. Frankincense, a widely recognized natural antitumor medicine, has undergone a systematic review encompassing its species, chemical constituents, and diverse pharmacological activities and mechanisms. The different species of frankincense include Boswellia serrata, Somali frankincense, Boswellia frereana, and Boswellia arabica. Various frankincense extracts and compounds exhibit antitumor, anti-inflammatory, and hepatoprotective properties and antioxidation, memory enhancement, and immunological regulation capabilities. They also have comprehensive effects on regulating flora. Frankincense and its principal chemical constituents have demonstrated promising chemoprophylactic and therapeutic abilities against tumors. This review provides a systematic summary of the mechanism of action underlying the antitumor effects of frankincense and its major constituents, thus laying the foundations for developing effective tumor-combating targets.
Keyphrases
  • anti inflammatory
  • small molecule
  • emergency department
  • stem cells
  • high throughput
  • mesenchymal stem cells
  • heat stress
  • drug induced
  • smoking cessation