A stochastic model of blood flow to calculate blood dose during radiotherapy.
Chris BeekmanJulia D WithrowCamilo M Correa-AlfonsoShreya PathakRobert J DawsonNatalia Carrasco-RojasAndrew SforzaCarlos ColonWesley E BolchClemens GrassbergerHarald PaganettiPublished in: Physics in medicine and biology (2023)
The ability to report the blood dose distribution during radiotherapy is imperative to test and act upon the current paradigm that radiation-induced lymphopenia is caused by direct cell killing of lymphocytes in the blood. We have built a general model that can do so for various treatment sites. The presented framework is publicly available at https://github.com/mghro/hedos.