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A Cohort Study of Adult Patients with Severe Dengue in Taiwanese Intensive Care Units: The Elderly and APTT Prolongation Matter for Prognosis.

Chih-Cheng HsiehCong-Tat CiaJen-Chieh LeeJunne-Ming SungNan-Yao LeePo-Lin ChenTe-Hui KuoJo-Yen ChaoWen-Chien Ko
Published in: PLoS neglected tropical diseases (2017)
During the 2015 dengue outbreak in Taiwan, the patients with severe dengue in ICUs were characterized by old age, multiple comorbidities, and a high CFR. Organ failure (including cardiac failure, and renal failure) and coagulation disturbance (prolongation of initial APTT) were independent predictive factors for in-hospital fatality.
Keyphrases
  • zika virus
  • aedes aegypti
  • dengue virus
  • drug induced
  • intensive care unit
  • early onset
  • healthcare
  • left ventricular
  • mechanical ventilation
  • adverse drug
  • acute care
  • community dwelling
  • extracorporeal membrane oxygenation