Excessive Mitochondrial Fission Suppresses Mucosal Repair by Impairing Butyrate Metabolism in Colonocytes.

Shi-Chen FuJun-Yan QuLi-Xiang LiXiao-Xiao YangYan-Qing LiXiu-Li Zuo

Published in: Inflammatory bowel diseases (2023)

Collectively, these data indicate that excessive mitochondrial fission suppresses mucosal repair by inhibiting butyrate metabolism and provides a potential target for mucosal healing in patients with ulcerative colitis.

Keyphrases

ulcerative colitis
signaling pathway
oxidative stress
weight gain
electronic health record
big data
body mass index
risk assessment
deep learning
weight loss
data analysis