Atrophic scar formation in patients with acne involves long-acting immune responses with plasma cells and alteration of sebaceous glands.

I CarlavanB BertinoM RivierP MartelV BourdesM MotteS DéretP ReinicheC MenigotA KhammariBrigitte DrenoP FogelJ J Voegel

Published in: The British journal of dermatology (2018)

Long-lived acne papules are characterized by a B-cell infiltrate. A relationship exists between the duration and severity of inflammation and the alteration of sebaceous gland structures, leading to atrophic scar formation in acne.

Keyphrases

hidradenitis suppurativa
immune response
induced apoptosis
oxidative stress
cell cycle arrest
wound healing
endoplasmic reticulum stress
dendritic cells
cell death
cell proliferation