Integrated analysis of long noncoding RNA-associated competing endogenous RNA network in periodontitis.

S LiX LiuH LiH PanAneesha AcharyaY DengY YuR HaakJ SchmidtG SchmalzDirk Ziebolz

Published in: Journal of periodontal research (2018)

These findings suggest that 6 mRNAs (HSPA4L, PANK3, YOD1, CTNNBIP1, EVI2B, ITGAL), 3 miRNAs (hsa-miR-125a-3p, hsa-miR-200a, hsa-miR-142-3p) and 3 lncRNAs (MALAT1, TUG1, FGD5-AS1) might be involved in the lncRNA-associated ceRNA network of periodontitis. This study sought to illuminate further the genetic and epigenetic mechanisms of periodontitis through constructing an lncRNA-associated ceRNA network.

Keyphrases

long noncoding rna
long non coding rna
dna methylation
network analysis
gene expression
cell proliferation
heat shock protein
nucleic acid