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Fabrication of a Cu Nanoparticles/Poly(ε-caprolactone)/Gelatin Fiber Membrane with Good Antibacterial Activity and Mechanical Property via Green Electrospinning.

Huakai ChenJinglin ZhangHaoping WuYongjun LiXiao LiJingxian ZhangLanghuan HuangSuiping DengShaozao TanXiang Cai
Published in: ACS applied bio materials (2021)
To improve the antibacterial effect of a poly(ε-caprolactone)/gelatin (PCL/Gt) composite, Cu nanoparticles (Cu NPs) were synthesized as an antibacterial agent, and a Cu NPs/PCL/Gt fiber membrane was thus fabricated via green electrospinning. The results showed that the Cu NPs/PCL/Gt fiber membrane with a uniform and complete structure exhibited high porosity and water absorption, favorable hydrophilicity, good mechanical and thermal properties, and satisfactory antibacterial activity. The easy preparation and good comprehensive property implied the great potential application of the Cu NPs/PCL/Gt fiber membrane in various fields ( e.g. , wound dressing and antibacterial clothing). In addition, the synthesis in this work would offer a promising approach for the preparation of a metal nanoparticle/polymer fiber material with good antibacterial property.
Keyphrases
  • silver nanoparticles
  • tissue engineering
  • aqueous solution
  • metal organic framework
  • wound healing
  • oxide nanoparticles
  • risk assessment
  • molecularly imprinted
  • simultaneous determination
  • walled carbon nanotubes