Impact of First-Line FOLFIRINOX-Induced Peripheral Neuropathy on the Efficacy of Second-Line GnP in Patients with Unresectable Advanced Pancreatic Cancer.

Shiori SadakaTakuji IwashitaHironori FujiiHiroko Kato-HayashiKoichi OhataShinya UemuraMasahito ShimizuAkio Suzuki

Published in: Journal of clinical medicine (2022)

mFFX-induced PN has little impact on the efficacy and safety of second-line GnP in patients with APC. Second-line GnP could be a possible treatment option regardless of the presence of PN.

Keyphrases

high glucose
diabetic rats
locally advanced
drug induced
oxidative stress
radiation therapy
rectal cancer
combination therapy