Adoptive transfer of placental ischemia-stimulated natural killer cells causes a preeclampsia-like phenotype in pregnant rats.

Olivia K TravisCedar BaikGeilda A TardoLorena M AmaralCarmilya JacksonMallory GreerChelsea GiachelliTarek IbrahimOwen T HerrockJan M WilliamsDenise C Cornelius

Published in: American journal of reproductive immunology (New York, N.Y. : 1989) (2020)

These data suggest a direct role for cNKs in causing preeclampsia pathophysiology and a role for normal NKs to improve maternal outcomes and IUGR during late gestation.

Keyphrases

physical activity
natural killer cells
early onset
pregnancy outcomes
pregnant women
preterm infants
electronic health record
metabolic syndrome
stem cells
big data
adipose tissue
birth weight
insulin resistance
preterm birth