Prevalence and Clinical Characteristics of Mitochondrial DNA Mutations in Korean Patients With Sensorineural Hearing Loss.

Sun Young Joo Seung Hyun Jang Jung Ah Kim Se Jin Kim Bonggi Kim Hye-Youn Kim Jae Young Choi Heon Yung Gee Jinsei Jung

Published in: Journal of Korean medical science (2023)

A significant proportion of Korean patients with hearing loss is affected by the mtDNA variants, with the m.1555A>G variant being the most prevalent. These results clarify the genetic basis of hearing loss in the Korean population and emphasize the need for genetic testing for mtDNA variants.

Keyphrases

copy number
mitochondrial dna
hearing loss
genome wide
dna methylation
risk factors