Egg excretion indicators for the measurement of soil-transmitted helminth response to treatment.
Piero L OlliaroMichel T VaillantAïssatou DiawaraBenjamin SpeichMarco AlbonicoJürg UtzingerJennifer KeiserPublished in: PLoS neglected tropical diseases (2022)
Combining the traditional efficacy assessment using group averages with individual responses provides a more complete picture of how anthelmintic treatments perform. Most treatments analyzed fail to meet the WHO minimal criteria for efficacy based on group means. Drug combinations (i.e., albendazole-ivermectin and albendazole-oxantel pamoate) are promising treatments for STH infections.
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