Circulating microRNAs as biomarkers in bile-derived exosomes of cholangiocarcinoma.
Jin-Yi HanKeun Soo AhnYong Hoon KimTae-Seok KimWon-Ki BaekSeong-Il SuhKoo Jeong KangPublished in: Annals of surgical treatment and research (2021)
Circulating miRNAs in bile-derived exosomes provide new information for the development of miRNA analysis in CCA. These miRNAs may represent the oncogenic characteristics of CCA tissue, enabling them to be used instead of tissue samples for the diagnosis of CCA. Further research investigating circulating miRNAs in bile exosomes may lead to more rational, targeted approaches to treatment.