Heart valve disease patients undergo multiple surgeries to replace structurally degraded valve prostheses, highlighting the need for valve replacements with growth and self-repair capacity. Given allogeneic valve transplantation's promise in meeting these goals by delivering a living valve replacement, we propose a framework for preserving and rehabilitating living valves ex vivo.
Keyphrases
- aortic valve
- mitral valve
- aortic stenosis
- aortic valve replacement
- ejection fraction
- congenital heart disease
- transcatheter aortic valve replacement
- transcatheter aortic valve implantation
- end stage renal disease
- heart failure
- newly diagnosed
- left ventricular
- chronic kidney disease
- bone marrow
- peritoneal dialysis
- machine learning
- low dose
- mesenchymal stem cells
- stem cells
- big data
- cell therapy
- hematopoietic stem cell