Stabilization of KPNB1 by deubiquitinase USP7 promotes glioblastoma progression through the YBX1-NLGN3 axis.

Jie LiBin ZhangZishan FengDandan AnZhiyuan ZhouChao WanYan HuYajie SunYijun WangXixi LiuWenwen WeiXiao YangJingshu MengMengjie CheYuhan ShengBian WuLu WenFang HuangYan LiKunyu Yang

Published in: Journal of experimental & clinical cancer research : CR (2024)

This study identified a novel and targetable USP7/KPNB1/YBX1/NLGN3 signaling axis in GBM cells.

Keyphrases

induced apoptosis
cell cycle arrest
oxidative stress
endoplasmic reticulum stress
cell death
pi k akt