A polymicrobial biofilm model for testing the antimicrobial potential of a nisin-biogel for canine periodontal disease control.

Our results showed that the nisin-biogel can inhibit and eradicate PD multispecies biofilms. As this in vitro model mimics an in vivo periodontal polymicrobial biofilm, our results reinforce the potential of the application of nisin-biogel for canine PD control.