Anti-heat shock protein 10 IgG in chronic spontaneous urticaria: Relation with miRNA-101-5p and platelet-activating factor.
Bo Youn ChoiEun-Mi YangHae-Won JungMin-Kyoung ShinJunghyun JoHyun-Young ChaHae-Sim ParkHo Chul KangYoung Min YePublished in: Allergy (2023)
A new autoantibody, anti-HSP10 IgG was detected in CSU patients, which showed a significant correlation with UAS7 scores. A decreased serum HSP10 level was associated with upregulation of miR-101-5p due to increased IL-4 and PAF in CSU patients. Modulation of miR-101-5p and HSP10 may be a novel therapeutic approach for CSU.