Glucocorticoid receptors α and β are modulated sex specifically in human placentas of intrauterine growth restriction (IUGR).
Stefan HutterPaula HeppSimone HofmannChristina KuhnJulia MessnerUlrich AndergassenDoris MayrMaria Emilia SolanoViola ObermeierSven MahnerPetra ArckUdo JeschkePublished in: Archives of gynecology and obstetrics (2019)
Our data support previous findings suggesting that the glucocorticoid metabolism plays a role in the pathophysiology of IUGR. Furthermore, the data suggest that the underlying molecular mechanisms differ between male and female cases.