Higher Serrated Polyp Detection Rates are Associated with Lower Risk for Post Colonoscopy Colorectal Cancer: Data From the New Hampshire Colonoscopy Registry.

Background We used New Hampshire Colonoscopy Registry (NHCR) data to examine the association between Post-colonoscopy colorectal cancer (PCCRC) and sessile serrated detection rates (SSLDR). Methods We included patients with either a colonoscopy or a CRC diagnosis in the NH State Cancer Registry. PCCRC, was any CRC diagnosed >/= 6 months after index exam. Results Of 26,901 patients, 162 were diagnosed with PCCRC. The hazard ratio for PCCRC was lowest for patients whose endoscopists had the highest SSLDR quintile (>6%) (HR=0.29;95%CI:0.16-0.50) Discussion Endoscopists with higher SSLDR had lower risks for PCCRC. These data validate SSLDR as a clinically relevant quality measure.