Fetal goiter identified in a pregnant woman with triiodothyronine-predominant graves' disease: a case report.
Akiko FujishimaAkira SatoHiroshi MiuraYuki ShimodaSaeko KameyamaChika AriakeHiroyuki AdachiYuki FukuokaYukihiro TeradaPublished in: BMC pregnancy and childbirth (2020)
The recommended perinatal management of Graves' disease is to adjust free T4 within a range from the upper limit of normal to a slightly elevated level in order to maintain the thyroid function of the fetus. However, in T3-predominant cases, free T4 levels may drop during the long-term course of the pregnancy owing to attempts to control the mother's symptoms of thyrotoxicosis. Little is known about the perinatal management and appropriate therapeutic strategy for T3-predominant cases and fetal goiter. Therefore, further investigation is necessary.