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Human lineage mutations regulate RNA-protein binding of conserved genes NTRK2 and ITPR1 involved in human evolution.

Wenxiang CaiWeichen SongShunying YuMin ZhaoGuan Ning Lin
Published in: General psychiatry (2024)
Our findings suggest that a small subset of human-specific mutations have contributed to human speciation through impacts on post-transcriptional modification of critical brain-related genes.
Keyphrases
  • endothelial cells
  • induced pluripotent stem cells
  • genome wide
  • resting state
  • binding protein
  • small molecule
  • functional connectivity
  • dna binding
  • heat shock