Human lineage mutations regulate RNA-protein binding of conserved genes NTRK2 and ITPR1 involved in human evolution.
Wenxiang CaiWeichen SongShunying YuMin ZhaoGuan Ning LinPublished in: General psychiatry (2024)
Our findings suggest that a small subset of human-specific mutations have contributed to human speciation through impacts on post-transcriptional modification of critical brain-related genes.