Incremental Yield of Including Determine-TB LAM Assay in Diagnostic Algorithms for Hospitalized and Ambulatory HIV-Positive Patients in Kenya.
Helena HuergaGabriella FerlazzoPaolo BevilacquaBeatrice KirubiElisa ArdizzoniStephen WanjalaJoseph SitieneiMaryline BonnetPublished in: PloS one (2017)
LAM should be included in TB diagnostic algorithms in parallel to microscopy or Xpert request for HIV-positive patients either ambulatory (severely ill or CD4<200cells/μl) or hospitalized. LAM allows same day treatment initiation in patients at higher risk of death and in those not able to produce sputum.
Keyphrases
- hiv positive
- end stage renal disease
- men who have sex with men
- antiretroviral therapy
- mycobacterium tuberculosis
- ejection fraction
- south africa
- newly diagnosed
- chronic kidney disease
- machine learning
- blood pressure
- high throughput
- peritoneal dialysis
- prognostic factors
- human immunodeficiency virus
- deep learning
- high resolution
- signaling pathway
- oxidative stress
- patient reported outcomes
- hiv infected
- hepatitis c virus
- endoplasmic reticulum stress
- pulmonary tuberculosis
- combination therapy