Sparing effect of tramadol, lidocaine, dexmedetomidine and their combination on the minimum alveolar concentration of sevoflurane in dogs.
Sayed Fathi El-HawariNorihiko OyamaYukako KoyamaJun TamuraTakaharu ItamiTadashi SanoKazuto YamashitaPublished in: Journal of veterinary science (2022)
Tramadol-lidocaine-dexmedetomidine co-infusion produced a remarkable sevoflurane MAC-sparing effect in clinically healthy beagle dogs and could result in the alleviation of cardiorespiratory depression caused by sevoflurane. Cardiorespiratory variables should be monitored carefully to avoid undesirable side effects induced by dexmedetomidine.